Sunday, January 24, 2010

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Swine flu predictions off on numbers

NEW YORK (UPI) -- America's sometimes patchy health surveillance system may have led officials to expect a more serious H1N1 epidemic than actually materialized, experts say.

Last week the Centers for Disease Control and Prevention said about 55 million people in the United States have come down with H1N1 and about 11,000 have died so far, The Wall St. Journal reported Saturday.

The death toll is far smaller than a White House report last summer predicted. It projected a scenario where 60 million to 120 million people would become sick in fall and winter 2009 with a projected total of 30,000 to 90,000 dying, the newspaper noted.

The estimates were based on outbreaks such as the one at the University of Delaware. Many students who exhibited flu-like symptoms did not seek treatment, and many who did weren't confirmed by lab tests, the Journal said.

Delaware was chosen as a test case because it represented an isolated outbreak, and CDC investigators were on hand to help gather and analyze data. But a student population with on-campus health service might not behave like the general public.

Researchers said very large numbers were being projected from very small ones.

"For all of these steps, we used the data we had available to us," said David Swerdlow, a CDC epidemiologist.

Marc Lipsitch, co-author of last summer's report projecting up to 90,000 deaths from swine flu and an epidemiologist at the Harvard School of Public Health said, "the data were limited and misleading and confusing."

Copyright 2010 by United Press International

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MS drug Ampyra approved for U.S. sale

WASHINGTON (UPI) -- The drug Ampyra has been approved for sale in the United States to aid walking in patients with multiple sclerosis, federal officials said.

The extended release drug, generically known as dalfampridine, has proven effective in increasing the walking speeds of people with MS, the U.S. Food and Drug Administration said in a release Friday.

"Trouble with walking is one of the most debilitating problems people with MS face," said Dr. Russell Katz, director of the FDA's Division of Neurology Products.

Ampyra, the first drug approved for this use, is manufactured by Elan of Dublin, Ireland,

MS is a chronic disease affecting the brain, spinal cord and optic nerves of about 400,000 people in the United States and 2.5 million people worldwide. The symptoms are unpredictable and vary from mild numbness in the limbs to paralysis, loss of vision, cognitive impairment and depression.

Ampyra's side effects include insomnia, dizziness, headache, nausea, weakness and back pain.

Copyright 2010 by United Press International

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Perceived discrimination affects smoking

INDIANAPOLIS (UPI) -- Minority teenage boys smoke more when they perceive discrimination but perceived discrimination did not increase smoking in girls, U.S. researchers say.

Indiana University School of Medicine researchers found there does not appear to be an association between perceived discrimination and smoking in minority girls, ages 12-15 -- but for minority girls ages 16-19, perceived discrimination is associated with lower, not higher, rates of smoking.

The researchers investigated 2,561 black and Latino adolescents, ages 12-19, from low-income households residing in Baltimore, Boston, Chicago, Los Angeles and New York.

One in four of the teens reported discrimination in at least one setting in the last six months. Twelve percent reported smoking in the last 30 days.

First author Dr. Sarah E. Wiehe, assistant professor of pediatrics at the Indiana University School of Medicine and a Regenstrief Institute affiliated scientist, said previous studies have found perceived racial/ethnic discrimination to be associated with adolescent and young adult smoking, but did not break down the linkage by gender.

The study is published online ahead of print of the March issue of the American Journal of Public Health.

Copyright 2010 by United Press International

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Plasma jets may replace dental drills

HOMBURG, Germany (UPI) -- Plasma jets that remove tooth decay-causing bacteria could be an effective and less painful alternative to the dentist's drill, German researchers said.

The study, scheduled to be published in the February issue of the Journal of Medical Microbiology, found firing low temperature plasma beams at dentin -- the fibrous tooth structure underneath the enamel coating -- was found to reduce the amount of dental bacteria by up to 10,000-fold.

Scientists at the Leibniz-Institute of Surface Modifications in Leipzig, Germany, and dentists at the Saarland University in Homburg, Germany, tested the effectiveness of plasma against common oral pathogens including Streptococcus mutans and Lactobacillus casei.

These bacteria form films on the surface of teeth and are capable of eroding tooth enamel and the dentin below it to cause cavities. If left untreated it can lead to pain, tooth loss and sometimes severe gum infections, the reseachers say.

Study leader Dr. Stefan Rupf of Saarland University said that the recent development of cold plasmas of temperatures of 40 degrees Celsius show great promise for use in dentistry.

Copyright 2010 by United Press International

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