| PHILADELPHIA (UPI) -- U.S. researchers suggest a breast cancer drug side-effect -- joint pain -- is linked to menopause.
The side-effect of sometimes very severe joint pain, arthralgia, was reported by 139 women of the 300 taking part in the study who were taking one of the drugs in a group of aromatase inhibitors.
Seventy-five percent of those reporting symptoms said the pain began within the first three months of the therapy.
"We are fortunate today to have many effective treatments for breast cancer. Unfortunately, many of these treatments have troublesome and debilitating side effects that can last for months or years after treatment, and really harm the quality of life and productivity of women who receive them," study lead author Dr. Jun J. Mao of the University of Pennsylvania School of Medicine in Philadelphia said in a statement.
The study, published in Cancer, found the joint pain was less likely in women who had experienced menopause more than a decade before taking the medication. Women who began the drug treatment less than five years after their last menstrual period were three times more likely to suffer arthralgia.
Copyright 2009 by United Press International
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| Kathy Mitchell and Marcy Sugar Dear Annie: I have a 9-year-old daughter who I love more than anything in this world. Her mother and I split up when she was 2. "Carrie" is an amazing girl, and we are very close. I try to spend as much time with her as possible. I know she wishes she had both of her parents all the time, and looking back, I wish things could have turned out differently, but it's too late now.
I have explained to Carrie that life doesn't always end up how we want, but her mother and I both love her very much. I encourage her to be open with me, but I get the impression that she is holding back.
I wish I had a clear idea of how to handle this situation properly for her sake. When I dropped her off at her mom's last night, she was fine until I was turning to leave, and then the tears started to pour. It kills me to see her so upset, and I feel helpless. The divorce has obviously taken its toll.
How can I help her accept that her parents will never be together? I am beginning to blame myself for her unhappiness because I am the one who left the marriage. After last night, I can't stop thinking about it and feel the need to do something. Any advice? -- Grateful but Worried Dad
Dear Grateful: Some children never give up the fantasy of having their divorced parents get back together. Showing Carrie how sad and guilty you feel gives her hope that she has influence over the outcome. The best thing you can do is help her adjust. See her as often as possible, show her that life is still wonderful, and be absolutely firm about your status. If she continues to burst into tears every time you drop her off at Mom's, please consider counseling for her.
Dear Annie: A woman who works with my husband has begun to send overly friendly e-mails to him. He also tells me she has been making passes at him at work.
My husband has tried to deal with the situation, and I trust him completely, but she continues to act inappropriately. I will be attending a company function with my husband soon, and this woman will be there. What can I say to her to let her know I'm aware of what's going on? I don't want to make a scene. -- Ticked-Off Wife
Dear Ticked Off: You should politely ignore her. Ending this situation is your husband's responsibility. He must make it abundantly clear to this woman that he is not interested, that he has informed you of the situation, that he would like her to cease and desist all such overtures, and that if she doesn't, he will report her to her superiors. If he refuses to do this, you have an entirely different problem.
Dear Annie: Regarding "Nervous Nick," whose wife stopped smoking a year ago and is now using nicotine gum -- talk to her!
I am on oxygen 24/7. I stopped smoking two years ago, and it is still hard to resist the urge for a cigarette. My lung function is 25 percent, but even right now, I would enjoy a smoke. You can't imagine how difficult it is for some of us to quit. It is a constant battle, so please talk to her, praise her for quitting, but don't overdo it.
I wish the truth could be told about emphysema. It is a slow, agonizing death. At first, breathing is shallow, and then it gets worse and you become weaker and weaker. I can only walk about 10 feet, and a gallon of milk is too heavy to carry. I can dress myself, but am not strong enough to take a shower.
In spite of this, I had two cigarettes in the last year. I am so ashamed. God gave me a strong, beautiful body, and I destroyed it. -- Granny in Southern California
Dear Granny: Nicotine is a highly addictive substance, and your letter proves how difficult it is to overcome. We'll be thinking of you.
Annie's Mailbox is written by Kathy Mitchell and Marcy Sugar, longtime editors of the Ann Landers column. Please e-mail your questions to anniesmailbox@comcast.net, or write to: Annie's Mailbox, P.O. Box 118190, Chicago, IL 60611. To find out more about Annie's Mailbox, and read features by other Creators Syndicate writers and cartoonists, visit the Creators Syndicate Web page at www.creators.com.
Copyright 2009 Creators Syndicate Inc.
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