Thursday, February 25, 2010

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Woman has babies after ovary transplant

COPENHAGEN, Denmark (UPI) -- A woman in Denmark gave birth to two children following an ovary transplant in what doctors are calling a medical first.

Claus Yding Andersen of the University Hospital of Copenhagen said so far, nine children have been born worldwide as a result of transplanting frozen/thawed ovarian tissue -- all in Europe.

Stinne Holm Bergholdt was diagnosed with Ewing's sarcoma when she was 27 in 2004. Before she began chemotherapy, part of her right ovary was removed and frozen -- her left ovary had been removed some years before because of a dermoid cyst, a type of benign ovarian tumor. Her cancer treatment was successful but, as expected, the drugs caused a menopause.

In December 2005 six thin strips of ovarian tissue were transplanted back on to what remained of her right ovary. Her ovary began to function normally again and, after mild ovarian stimulation, she became pregnant and gave birth to her first daughter, Aviaja, in February 2007, and in 2008 she had conceived a second child naturally and gave birth to another girl in September 2008.

"This showed that the original transplanted ovarian strips had continued to work for more than four years and that Mrs. Bergholdt still has the capacity to conceive and give birth to healthy children," Andersen said in a statement.

The findings are published in the journal Human Reproduction.

Copyright 2010 by United Press International

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WHO: Premature to say H1N1 has peaked

GENEVA, Switzerland (UPI) -- It is premature to conclude that all parts of the world have experienced peak transmission of H1N1, World Health Organization officials in Switzerland say.

The emergency committee, which makes recommendations to Dr. Margaret Chan, director general of WHO, held its seventh meeting on the determination of the pandemic status.

The committee was provided a detailed analysis of the pandemic worldwide and after asking additional questions and reviewing the evidence and holding extensive discussion, the committee said there was mixed evidence showing declining or low pandemic activity in many countries.

WHO officials say there is new community level transmission activity in West Africa and the committee expressed concern that the winter months of the Southern Hemisphere had not yet started and there was uncertainty whether additional generalized waves of H1N1 activity might occur. Therefore, there is a need not to undermine preparations, the officials say.

The committee advised that it was premature to conclude that all parts of the world have experienced peak transmission of the H1N1 pandemic influenza and that additional time and information was needed to provide expert advice on the status of the pandemic.

Copyright 2010 by United Press International

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Magnesium may be vital to memory

TEL AVIV, Israel (UPI) -- An Israeli researcher says sufficient magnesium is key to memory function, but relying on supplements may not be of much help.

Dr. Inna Slutsky of Tel Aviv University's Sackler School of Medicine says magnesium must penetrate the blood-brain barrier to help stave off age-related memory loss.

Slutsky's research, begun at the Massachusetts Institute of Technology as part of a post-doctoral project, has spurred multicenter experiments focusing on a synthetic magnesium that does penetrate the blood-brain barrier -- magnesium L-theronate.

Study findings for the five-year period of experiments using rats found the synthetic magnesium compound enhanced memory or prevented memory impairment in both young and aging animals.

"We are really pleased with the positive results of our studies" using the synthetic magnesium compound, Slutsky said in a statement. "But on the negative side, we've also been able to show that today's over-the-counter magnesium supplements don't really work. They do not get into the brain."

Before synthetic magnesium becomes available, Slutsky recommends getting more magnesium the old-fashioned way -- by eating lots of greens, broccoli, almonds, cashews and fruit.

The findings are published in Neuron.

Copyright 2010 by United Press International

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Napping can make you smarter

SAN DIEGO (UPI) -- An hour's nap can dramatically boost and restore brain power, not only refreshing the mind, but making a person smarter, U.S. researchers found.

Lead investigator Matthew Walker, an assistant professor of psychology at the University of California, Berkeley, also found the more hours people spend awake, the more sluggish the mind becomes.

The results support previous data from the same research team that showed pulling an all-nighter decreases one's ability to cram in new facts by nearly 40 percent because some brain regions shut down during sleep deprivation.

The study involved 39 healthy young adults divided into two groups -- nap and no nap. At noon, all the participants were subjected to a rigorous learning task intended to tax the hippocampus, a region of the brain that helps store fact-based memories. Both groups performed at comparable levels.

At 2 p.m., the nap group took a 90-minute siesta while the no-nap group stayed awake. At 6 p.m., participants performed a new round of learning exercises.

Those who remained awake throughout the day became worse at learning; those who napped did markedly better and actually improved in their capacity to learn.

The findings were presented at the annual meeting of the American Association of the Advancement of Science in San Diego.

Copyright 2010 by United Press International

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