Dear R help My problem is very similar to the analysis detailed here. If we use the mayo dataset provided with the survivalROC package the estimate for Somer's Dxy is very negative -0.56. The Nagelkerke R2 is positive though 0.32. I know there is a difference between explained variation and predictive ability but I am surprised there is usch a difference given that even a non predictive model should have Dxy around 0. Am I doing something wrong or is there an interpretation that makes sense ? This is with the mayo data so its reproducible but the result with my data is very similar. Many thanks in advance library(survivalROC) library(Design) library(survival) data(mayo) Sm <- Surv(mayo$time,mayo$censor) fm <- cph( Sm ~ mayoscore4 ,mayo,x=T,y=T,surv=T ) validate(fm, B=150,dxy=T) Iteration 1 .... index.orig training test optimism index.corrected n Dxy -0.566027923 -0.566665407 -0.566027923 -0.0006374833 -0.565390440 150 R2 0.325860603 0.327350885 0.325860603 0.0014902826 0.324370320 150 Slope 1.000000000 1.000000000 0.987854765 0.0121452354 0.987854765 150 D 0.093398440 0.095166239 0.093398440 0.0017677983 0.091630642 150 U -0.001562582 -0.001579618 0.001150175 -0.0027297932 0.001167211 150 Q 0.094961022 0.096745857 0.092248266 0.0044975915 0.090463431 150 Dr Bernard North Statistical Consultant Statistical Advisory Service Advice and Courses on Research Design and Methodology Imperial College South Kensington Campus Room 845, 4th Floor 8 Princes Gardens London SW7 1NA. Tel: 020 7594 2034 Fax: 020 7594 1489 Email: bno ... @ Web: [[alternative HTML version deleted]] ______________________________________________ R-h ... @ mailing list PLEASE do read the posting guide and provide commented, minimal, self-contained, reproducible code